Matteo Iannacone graduated in Medicine magna cum laude at University of Milan, and performed his PhD in Immunology at Vita-Salute San Raffaele University in Milan. From 2001 and 2003 he moved as a post-doctoral fellow in Luca Guidotti and Frank Chisari’s group at Scripps Research Institute in La Jolla. After that he return back in San Raffaele Institute in Milan as Resident in internal medicine. From 2007-2010 he was a post-doc in Hulrich Von Andrian Lab at Harvard. Since 2010, he is group leader at San Raffaele Scientific Institute where since 2015 isheading the Dynamics of Immune responses Lab.
Iannacone has contributed to the field of anti-viral immune responses, lately making magistral use of intra-vital microscopy techniques. He was the first to show that during hepatitis B virus-associated hepatitis, activated platelets are required to recruit virus-specific cytotoxic T lymphocytes into the liver, contributing to disease severity and viral clearance. Later he discovered a previously undetected B cells boosting activities of bisphosphonates. Recently, making magistral use of Intra vital microscopy, his team is focusing in studying the mechanisms that viruses exploit to interfere with adaptive immune responses opening the possibility to design novel, more rational vaccine and therapeutic strategies. Throughout his career, he earned many prestigious awards and grants. He has been involved in the organization of several prestigious international meetings on viral immunity among them the 1st European Molecular Biology Organization (EMBO) Sectoral Meeting on Immunology in Bergamo in 2017. He holds an Armenise-Harvard Foundation Carreer Development award, an EMBO Young Investigator Award, and ERC starting and consolidator grants. He is an Invited Section Editor of Current Opinion in Virology.